During this video Dr. Mary Clifton speaks about how THC and cannabis could stave off colon cancer, but the current research is very minimal. There are 97,000 new cases per year, 50,000 deaths each year, making colorectal cancer the third most common cancer cause of death in the United States.
What you’ll Learn
- Statistics of Colon Cancer
- Advanced Screening and other preventive measures
The Reality of Colon Cancer and How it Relates to Cannabis
Colon cancer. A subject that is near and close to my heart, given that I lost of my older brothers to colon cancer. There’s 97,000 new cases per year, 50,000 deaths each year, making colorectal cancer the third most common cancer cause of death in the United States. Although there has been some reduction in mortality caused by colorectal cancer due to advances in screening, preventive colonoscopy, it still remains the third most common cancer diagnoses. But the good news, if there is any around colorectal cancer, is that the changes in the colonic epithelial cells are very slow in general, and typically take up to five years to go from normal cells to a adenomatous polyp of precancerous foci. Oftentimes there’s the development of a small area, an aberrant crypt foci, of abnormal cells that then develops into a polyp.
Further research is working on the prevention of the development in these polyps, adenomatous polyps being identified as precancerous. Then also doing the polypectomies. But of course, chemoprevention can help. Before you get to your colonoscopy, this is one cancer that’s going to respond very well to eating a good diet and following a healthy lifestyle, but in addition to that, THC has been shown to be potentially beneficial in a laboratory setting. In fact, THC induces cell death in these aberrant cryptic foci in a CB1 dependent way, by stimulating the CB1 receptors on the epithelial cells. That stimulation seems to work to induce cell death through the reactive oxygen species pathway, the ROS pathway.
Could THC, regular cannabis use, actually stave off colon cancer? Well, this is very early research to suggest that that may be possible, and I don’t know of any studies that are ongoing that are looking at people who are using cannabis versus people who aren’t to determine if there’s a reduction in colorectal cancer, but stay tuned. This data on the way that THC is working with cancer cells in the laboratory is, I think, very interesting, surrounding colorectal cancer, and may shed some light on how THC and other cannabinoids can help to reduce the risk of cancer for a healthy person who is regularly using.
Dr. Mary Clifton
She provides specialized consultation on patient and provider education, telemedicine and cannabinoids, and has worked with several pharmaceutical, CBD and cannabis corporations on areas of product development, speakers bureau, spokesperson, telemedicine, medical and scientific directorship.
Dr. Clifton is the bestselling author of “The Grass Is Greener: Medical Marijuana, THC & CBD OIL: Reversing Chronic Pain, Inflammation and Disease” and “Get Waisted”, as well as five companion cookbooks. She speaks at major cannabinoid events around the world, including Africa, Europe and Asia.