During this discussion Dr. Mary Clifton speaks about the the many ways that CBD and cannabis could be working to help your chemotherapeutic agents be most effective at fighting your cancer.


What you’ll Learn

  • PGP Pumps
  • CBD & Cannabis for Cancer

The Benefits of CBD with PGB Pumps & Cancer


There are a number of ways in which CBD and cannabis could be working to help your chemotherapeutic agents be most effective at fighting your cancer, but the most interesting way I think is through the effect of cellular pumps. A CBD can inhibit a variety of transporters and cytochrome enzymes in the liver that could be impacting, altering the dosage levels of anticancer therapy. It’s important that if you’re using these agents in combination with your chemotherapy, that you talk to your oncologist about that.

But many cancer cells over time, become resistant to anticancer therapies because of these Pgp pumps. These are pumps that are present on the cell’s surface that help to pump out toxins, and as the pumps get more and more exposure to these toxic chemotherapy regimens, that are toxic because they need to kill the cancer cells, the cells get smarter and smarter at getting rid of the toxins faster. These Pgp pumps become more and more effective at pumping out the chemotherapy quickly, and then the cancer cell can stay alive, unfortunately, even if it’s surrounded by chemotherapy agents.

CBD is found to have an inhibitory effect on the Pgp pumps, and that could theoretically mean that cancer cells would not be as successful as getting those anticancer agents out of the cells, with exposure to CBD. This knowledge could affect the way anticancer cells are dosed, and how much anticancer agents are going to be needed, as well as affecting overall patient outcomes. The way by which CBD interacts with these pumps could be a major advancement for combating the resistance of cancer cells to chemotherapy.

Now don’t forget, there’s other ways that CBD interacts with your body, including these cytochrome systems in the liver. Make sure that if you’re using these products, you let your oncologist know, so that they can provide you the best cancer care that they have available for you.

Dr. Mary Clifton


Dr. Mary Clifton is an Internal Medicine doctor in New York City, with 20 years of experience in both the hospital and private practice and is also a licensed by the New York State Department of Health to provide medical marijuana and is a recognized expert in CBD, Cannabis, and Medical Marijuana.

She is a published researcher, national speaker on women’s health and osteoporosis, and author of four books, and two new soon-to-be-released books on CBD and Cannabis – what you need to know, how to use them and a COOKBOOK to support ease of use.